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Relationship between morbidity and hypo- normo- and hypervolemia. Bellamy [17] developed a theoretical framework based on their concept that there is a U-shape relationship between fluid therapy and outcome. Therefore, prevention of hypo- and hypervolemia by goal-directed fluid management is essential. SIRS: systemic inflammatory response syndrome, MOV: multiple organ failure, PONV: postoperative nausea and vomiting.
