Fig. 3.

The effects of BMS-470539 on nuclear translocation of nuclear factor kappa B (NF-κB) in human neutrophils stimulated by lipopolysaccharide (LPS).

Neutrophils (5 × 10⁶/ml) from human blood were incubated for 30 min without or with BMS-470539 (100 µM), or with LPS (100 ng/ml) or LPS plus BMS-470539 (Control, BMS, LPS, LPS + BMS, respectively). The phosphorylation level of NF-κB was measured by ELISA. Values are presented as mean ± SD (n = 4 per group). ^*P < 0.05 versus with Control, ^†P < 0.05 versus LPS.