| Prognostic scores: key points |
| • New scoring systems have been recently developed for PMF (MIPSS70) and SMF (MYSEC-PM) prognostication, and for transplant outcome (MTTS). |
| • Still, IPSS and DIPSS are widely used in clinical practice and for the transplant-decision process, although the MYSEC-PM score has been proved to be more accurate in SMF patients. |
| • Impact of subclonal mutations in SMF deserves confirmation. |
| • The weight of prognostic variables in patients treated with JAK inhibitors has not been still assessed prospectively. |
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