Fig. 4.

ID1 is downregulated during DC maturation. a Flow cytometric analysis of human monocytes and monocyte-derived dendritic cells. Density plots indicate CD80 and CD86 expression of monocytes and dendritic cells matured with various cocktails of immunostimulatory compounds, leading to well-described types of maturation. b Expression of ID1, and more established markers used for characterization of monocytic MDSC, during myeloid cell maturation to a fully immunogenic phenotype associated with the indicated models for differentiation of human monocytes to mature dendritic cells