Table 3.

The level of methylation connected with HPV status

Gene	HPV status	Methylation	References
CDH18	+	↑	Degli Esposti et al. (2017)
CTNND2	+	↑	Degli Esposti et al. (2017)
ELMO1	+	↑	Degli Esposti et al. (2017)
CDH8	+	↑	Degli Esposti et al. (2017)
CRMP1	+	↑	Degli Esposti et al. (2017)
PCDH10	+	↑	Degli Esposti et al. (2017)
MSX2	+	↑	Degli Esposti et al. (2017)
SYN2	+	↑	Degli Esposti et al. (2017)
PCDHB11	+	↑	Degli Esposti et al. (2017)
HTR1E	+	↑	Degli Esposti et al. (2017)
CCNA1	+	↑	Colacino et al. (2013) and Virani et al. (2015)
GRB7	+	↑	Colacino et al. (2013)
CDH11	+	↑	Colacino et al. (2013)
RUNX1T1	+	↑	Colacino et al. (2013)
SYBL1	+	↑	Colacino et al. (2013)
TUSC3	+	↑	Colacino et al. (2013)
MINT31	+	↑	Choudhury and Ghosh (2015)
NDN	+	↑	Virani et al. (2015)
CD1A	+	↑	Virani et al. (2015)
DCC	+	↑	Virani et al. (2015)
CADM1	+	↑	van Kempen et al. (2014)
TIMP3	+	↑	van Kempen et al. (2014)
ADORA2	+	↑	Vogt et al. (2018)
NCAN	+	↓	Degli Esposti et al. (2017)
NRXN1	+	↓	Degli Esposti et al. (2017)
COL19A1	+	↓	Degli Esposti et al. (2017)
SYCP2	+	↓	Degli Esposti et al. (2017)
RPA2	+	↓	Degli Esposti et al. (2017)
SMC1B	+	↓	Degli Esposti et al. (2017)
SPDEF	+	↓	Colacino et al. (2013)
STAT5A	+	↓	Colacino et al. (2013)
MGMT	+	↓	Colacino et al. (2013)
ESR2	+	↓	Colacino et al. (2013)
JAK3	+	↓	Colacino et al. (2013)
HSD17B12	+	↓	Colacino et al. (2013)
p16	+	↓	Virani et al. (2015)
	+	↑	Choudhury and Ghosh (2015)
RASSF1	+	↓	Colacino et al. (2013)
	+	↑	Choudhury and Ghosh (2015)
NT5E	+	↓	Vogt et al. (2018)
CHFR	−	↑	van Kempen et al. (2014)
PAX1	−	↑	Guerrero-Preston et al. (2014)
PAX5	−	↑	Guerrero-Preston et al. (2014)
CDH13	±	↑	van Kempen et al. (2014)
RARB	±	↑	van Kempen et al. (2014)
DAPK	±	↑	van Kempen et al. (2014)
	+	↑	Choudhury and Ghosh (2015)
LINE1 seguences	+	↑	Furlan et al. (2017)
	-	↓	Richards et al. (2009)

“+” HPV-positive; “−” HPV-negative; “↑” hypermethylation; “↓” hypomethylation