Fig. 4.

Proportions of patients achieving clinical response (PP population). ACR20, ACR50, and ACR70 are the proportion of the patients with at least 20%, 50%, or 70% improvement in counts of tender and swollen joints and in 3 of the following: patient’s assessment of pain, patient’s global assessment of disease activity, patient’s assessment of physical function, the physician’s global assessment of disease activity, and acute phase reactant. ACR American College of Rheumatology, PP per-protocol, RTX-EU MabThera^®, RTX-US Rituxan^®