Table 4.
Comparison of variables associated with “malnutrition” defined by a low GNRI category or a low Cr index category.
| Variables | Adjusted odds ratio (95% CI) for a low GNRI category | P-value | Adjusted odds ratio (95% CI) for a low Cr index category | P-value |
|---|---|---|---|---|
| Normalized protein catabolic rate, per 1 g/kg/day increase | 0.34 (0.19, 0.63) | 0.001 | 0.05 (0.02, 0.10) | <0.001 |
| Body mass index, per 1 kg/m2 increase | 0.71 (0.68, 0.75) | <0.001 | 0.91 (0.87, 0.94) | <0.001 |
| Serum Cr, per 1 mg/dL increase | 0.83 (0.78, 0.87) | <0.001 | — | — |
| Serum albumin, per 1 g/dL increase | — | — | 0.42 (0.31, 0.58) | <0.001 |
| Serum CRP, per 1 mg/dL increase | 1.00 (1.00, 1.01) | 0.07 | 1.00 (1.00, 1.00) | 0.99 |
A low GNRI was defined as the patients in the lowest quartile (Q1) of GNRI. A low Cr index was defined as the patients in the lowest quartile (Q1) of Cr index. AUCs calculated by multivariable adjusted logistic regression analysis for GNRI and Cr index were 0.814 (0.793 to 0.835) and 0.900 (0.885 to 0.913), respectively. Age, sex, dialysis vintage, history of diabetes mellitus and cardiovascular disease, and single-pool Kt/V for urea, use of vitamin D receptor activators and phosphate binders were also included in the multivariable-adjusted logistic regression analysis. A P-value less than 0.05 was considered statistically significant. Abbreviations: AUC, area under the curve; CI, confidence interval; Cr, creatinine; CRP, C-reactive protein; GNRI, geriatric nutritional risk index.