Table 2.

A summary of the main findings for exacerbations.

Author (year) sample size	Type of exacerbation reported	Group allocation
		Intervention	Control
Liu (2008) Intervention N = 24, Control N = 24	Managed in the community, N; p = NS	F: N = 4	F: N = 26
	Leading to hospitalization, N; p = NS	F: N = 2	F: N = 22
Halpin (2011) Intervention N = 40, Control N = 39	Clinical exacerbation frequency, mean (SD); p = NS	F: 0.95 (1.71)	F: 1.17 (1.81)
Chau (2012) Intervention N = 22, Control N = 18	Managed in the community, N; p = NS	F: N = 7	F: N = 3
	Leading to hospitalization, mean (SD) or N; p = NS	B: 2.41 (1.57) F: N = 7	B: 2.89 (2.32) F: N = 3
Pinnock (2013) Intervention N = 8, Control N = 8	Leading to hospitalization, mean (SD); p = NS	F: 1.5 (2.3)	F: 1.3 (1.8)
	Managed in the community, mean (SD); p = NS	F: 15 (12.7)	F: 12.8 (11.8)
Farmer (2017) Intervention N = 110, Control N = 56	Unspecified, median (IQR); p = NS	F: 1 (0–2)	F: 1 (0–3)

B baseline, F follow-up, IQR interquartile range, N number of participants, NS nonsignificant, SD standard deviation.