Table 2.

Experimental groups immunized with different vaccine formulations.

Groups	Compound (100 μl)	Abbreviate
1	pDNA-surface localized archaeosome	pDNA + (S)Arch
2	pDNA-encapsulated archaeosomes	pDNA + (E)Arch
3	pDNA alone (L1/E6/E7 recombinant gene)	pDNA
4	archaeosomes alone (antigen-free archaeosomes)	Arch
5	pIRES (Control group)	Mock Plasmid
6	PBS (Control group)	PBS

The vaccine dose per mice injected as follows:

Dose of pDNA alone (L1/E6/E7 recombinant gene): 50 µg; Dose of archaeosomes alone (antigen-free archaeosomes): 1 mg; Dose of Archeasome/DNA mixture: pDNA-surface localized archaeosome AND pDNA-encapsulated archaeosomes: 1 mg of Archeasome containing 50 µg of pDNA.

Days of immunization (Days after TC1 inoculation): 7, 14, and 21.

Route of administration: Subcutaneous.