Table 1.
General characteristics of experimental groups.
| NDM SD | DM SD | DM SD + Lina | |
|---|---|---|---|
| Number | 5 | 3 | 4 |
| Body weight (g) | 418.5 ± 31.4 | 333.3 ± 31.8** | 289.6 ± 22.6** |
| Blood glucose (mg/dL) | 102.2 ± 6.9 | 398.0 ± 95.3** | 433.0 ± 82.1** |
| rKW/BW (g/100 g BW) | 0.80 ± 0.10 | 1.20 ± 0.27* | 1.26 ± 0.20* |
| UAE (µg/mg Cr) | 95.6 ± 73.7 | 695.9 ± 207.8** | 439.1 ± 60.3** # |
| Serum insulin (ng/mL) | 3.32 ± 0.62 | 0.90 ± 0.16** | 0.75 ± 0.13** |
NDM SD, nondiabetic model Sprague-Dawley; DM SD, diabetic model Sprague-Dawley; Lina, linagliptin; rKW/BW, right kidney weight/body weight; UAE, urinary albumin excretion. Data expressed as means ± SD. *P < 0.05, **P < 0.01 vs. NDM SD, #P < 0.05 vs. DM SD.