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. 2020 Apr 1;10:5770. doi: 10.1038/s41598-020-62404-1

Figure 4.

Figure 4

Different areas of chips after solid phase PCR. (a) Digital areas show where the process of the PCR worked well and no leakage or drying-ins of the cavities occurred. (b) Leakage can form through defects in the mold, incomplete sealing or non-uniform pressure during the PCR process. (c) Drying-ins can only be observed on chips which were processed in the slide cycler because of water evaporations at the chip edges.