Table 1.
Patient characteristics
| Variable | All (n = 770) | No cardiac event (n = 704) |
Cardiac event (n = 66) |
pa |
|---|---|---|---|---|
| Male gender | 493 (64%) | 452 (64%) | 41 (62%) | NS |
| Age at transplant (mean ± SD) | 54.3 ± 13.9 | 53.4 ± 14.0 | 63.0 ± 9.6 | <0.001 |
| Age above 60 | 309 (40%) | 264 (38%) | 45 (68%) | <0.001 |
| Delayed graft function | 174 (23%) | 149 (21%) | 25 (38%) | 0.001 |
| Living donor | 532 (69%) | 499 (71%) | 33 (50%) | 0.001 |
| Dialysis before kidney transplantation | 522 (68%) | 468 (66%) | 54 (82%) | 0.001 |
| Dialysis duration longer than 1 year | 374 (49%) | 331 (47%) | 43 (65%) | 0.004 |
| History of cardiac disease | 139 (18%) | 100 (14%) | 39 (59%) | <0.001 |
| – Intervention | 86 (11%) | 62 (9%) | 24 (36%) | <0.001 |
| – MI | 81 (11%) | 53 (8%) | 28 (42%) | <0.001 |
| – Heart failure | 46 (6%) | 28 (4%) | 18 (27%) | <0.001 |
| History of diabetes | 186 (24%) | 163 (23%) | 23 (35%) | 0.049 |
| History of stroke | 79 (10%) | 67 (10%) | 12 (18%) | 0.03 |
| History of peripheral artery disease | 56 (7%) | 43 (6%) | 13 (20%) | <0.001 |
| History of smoking | 146 (18%) | 136 (19%) | 10 (15%) | NS |
| History of hypertension | 678 (88%) | 622 (88%) | 56 (85%) | NS |
| History of LVH | 82 (11%) | 74 (11%) | 8 (12%) | NS |
| History of hypercholesterolaemia | 338 (44%) | 313/702 (45%) | 25/65 (38%) | NS |
| Three or more risk factors | 465 (60%) | 407 (53%) | 58 (88%) | <0.001 |
| Non-invasive ischaemia testing | ||||
| – Abnormal MPS | 93/279 (33%) | 69/241 (29%) | 24/38 (62%) | <0.001 |
| – Abnormal EST | 9/328 (3%) | 8/302 (3%) | 1/26 (4%) | NS |
| – Abnormal DSE | 1/64 (2%) | 1/61 (2%) | 0/3 (0%) | NS |
| Coronary angiography | 85 (11%) | 75 (11%) | 10 (15%) | NS |
| Significant CAD on angiography | 19 (2%) | 18 (3%) | 1 (2%) | NS |
| Difference in haemoglobin level (mmol/l, mean ± SD) | −2.2 ± 1.0 | −2.1 ± 1.0 | −2.6 ± 1.0 | <0.001 |
All data are n (%) unless stated otherwise
Tx transplantation, MI myocardial infarction, LVH left ventricular hypertrophy, MPS myocardial perfusion scintigraphy, EST exercise stress testing, DSE dobutamine stress echocardiography, CAD coronary artery disease
aNo cardiac event versus cardiac event