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. 2020 Mar 26;11:265. doi: 10.3389/fgene.2020.00265

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Copyright © 2020 Wang, Chen, Rao and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CTNND1 splicing outcomes influenced by modulator expression in KIRC. (A) Examples of modulators in each mode sub-categories, including exon exclusion to inclusion (ExonEI), exon inclusion to exclusion (ExonIE), enhances exon exclusion (EEE) and attenuates exon exclusion (AEE). (B) Four modulators influence splicing outcomes of CTNND1, including TNFRSF14, ARMH4, LAPTM4B, and ODF3B. The red means the samples in modulator expression high group (top 33%), the blue means the samples in modulator expression low group (bottom 33%). The x-axis is the expression level of QKI, y-axis is splicing outcome (PSI value) of CTNND1.