TABLE 3.
Results of ANOVA and multiple comparisons.
Parameters | Testing time (time post de- compression) | ANOVA | Post Hoc Tests | |||
df | F | P | Groups (vs. Saline group) | P | ||
W/D weight ratio | 24 h | 4 | 4.120 | 0.007 | UTI-H | 0.034 |
UTI-M | 0.352 | |||||
UTI-L | 0.693 | |||||
Normal | 0.001 | |||||
BALF Protein | 24 h | 4 | 5.492 | 0.001 | UTI-H | 0.012 |
UTI-M | 0.498 | |||||
UTI-L | 0.675 | |||||
Normal | 0.001 | |||||
WBC | 1 h | 3 | 2.928 | 0.049 | UTI-H | 0.006 |
UTI-M | 0.066 | |||||
UTI-L | 0.134 | |||||
PLT | 1 h | 3 | 3.047 | 0.043 | UTI-H | 0.005 |
UTI-M | 0.065 | |||||
UTI-L | 0.160 | |||||
IL-1β | 6 h | 3 | 7.195 | 0.000 | UTI-H | 0.001 |
UTI-M | 0.018 | |||||
UTI-L | 0.999 | |||||
MCP-1 | 12 h | 3 | 6.897 | 0.000 | UTI-H | 0.002 |
UTI-M | 0.106 | |||||
UTI-L | 0.181 | |||||
ET-1 | 12 h | 3 | 9.554 | 0.000 | UTI-H | 0.001 |
UTI-M | 0.011 | |||||
UTI-L | 0.340 | |||||
ICAM-1 | 12 h | 3 | 13.733 | 0.000 | UTI-H | 0.000 |
UTI-M | 0.000 | |||||
UTI-L | 0.022 | |||||
MDA | 6 h | 3 | 5.560 | 0.002 | UTI-H | 0.001 |
UTI-M | 0.174 | |||||
UTI-L | 0.806 | |||||
MPO | 1 h | 3 | 2.799 | 0.047 | UTI-H | 0.006 |
UTI-M | 0.083 | |||||
UTI-L | 0.273 |
Rabbits were subjected to simulated diving to 6 atmospheres absolute (ATA) for 60 min with 2.5-minute decompression, and received intravenous injection of different doses of UTI or saline immediately following decompression. Lung tissues and BALF were sampled for determination of W/D weight ratio and protein content, respectively. Blood was sampled for WBC, PLT and serum indices including IL-1β, MCP-1, ET-1, ICAM-1, MDA, and MPO. Values of the indices were compared between the Saline group and UTI groups at different time points.