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. 2020 Mar 26;11:221. doi: 10.3389/fgene.2020.00221

TABLE 3.

Performance of the survival prediction models based on Clinical Characteristics and 24 HLA-Class I, II Superalleles implemented using various regression techniques.

Method Feature Set-1 Feature Set-2


All Features

HR P-value HR P-value
LASSO 3.17 3.50E-11 4.05 4.01E-13
RIDGE 3.01 1.76E-10 3.80 2.30E-12
RF 3.09 2.87E-11 3.77 8.15E-12
DT 2.25 6.93E-07 2.00 5.29E-05
Clinical features without tumor status
LASSO 3.50 3.93E-13 3.46 1.54E-11
RIDGE 3.49 3.93E-13 2.97 2.89E-09
RF 3.74 3.01E-14 2.96 8.23E-10
DT 2.15 2.24E-06 1.83 3.12E-04
Clinical features without tumor stage
LASSO 2.80 9.96E-10 3.51 1.32E-11
RIDGE 2.43 4.68E-08 3.55 7.56E-12
RF 2.81 2.05E-10 3.18 2.14E-10
DT 2.50 1.64E-08 2.76 2.38E-09
Clinical features without tumor stage and tumor status
LASSO 2.40 4.41E-08 3.11 5.60E-10
RIDGE 2.40 4.41E-08 2.57 5.81E-08
RF 2.99 9.37E-12 2.59 1.55E-08
DT 2.54 1.06E-08 2.65 7.37E-09

#HR: Hazard Ratio; RF: Random Forest; DT: Decision Tree; Feature Set-1: Clinical and demographic features, Feature Set-2: Clinical, demographic and 24 HLA superalleles features.