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. 2020 Mar 21;32:101514. doi: 10.1016/j.redox.2020.101514

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© 2020 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 1 — Exogenous spermine inhibits STZ-induced myocardial injury in DCM rats. STZ (60 mg/kg) was injected into the abdominal cavity of rats to establish the model of T1D and the related indexes were determined 12 weeks later. (a) blood glucose concentration, (b) serum triglyceride concentration, (c) serum cholesterol concentration, (d) serum insulin concentration, (e) body weight, (f) heart weight/body weight, (g) cardiac function, (h) serum cTnT concentration, (i) serum LDH concentration, (j) serum CK-MB concentration, (k) serum GSP concentration, (l) myocardial histomorphology, (m) myocardial fibrosis level, (n) SOD2 concentration, (o) MDA concentration, and (p) CAT concentration were detected. *, P < 0.05 versus Control group; #, P < 0.05 versus T1D group.