Figure 3.
Box‐and‐whisker plots showing that the expression of (A) miR‐424‐5p, (B) miR‐424‐3p, and (C) miR‐450a‐5p is increased and the expression of (D) miR‐451a and (E) miR‐144‐5p is decreased in non‐small cell lung cancer (NSCLC) patients with cachexia compared with control. The expression of the microRNAs was determined by quantitative PCR in vastus lateralis muscle biopsies from the extended cohort of cachectic (n = 15) and non‐cachectic (n = 11) NSCLC patients and healthy controls (n = 22) as described in the Methods section. The box‐and‐whisker plot shows median and min to max. * P < 0.05 and *** P < 0.001, Kruskal–Wallis test and Dunn post hoc testing.