Table 3.
Comparison of the original (EWGSOP 1) and revised (EWGSOP 2) European consensus for sarcopenia and the new sarcopenia phenotype score (SPS) in predicting a composite endpoint of mortality and institutionalization due to functional impairment
Model 1 | Model 2 | Model 3 | |||||
---|---|---|---|---|---|---|---|
HR | 95% CI | HR | 95% CI | HR | 95% CI | ||
EWGSOP 1 | |||||||
No sarcopenia | (ref) | ||||||
Sarcopenia | 3.76 | 2.66–5.31 | 2.29 | 1.56–3.36 | 2.19 | 1.50–3.22 | |
EWGSOP 2 | |||||||
No sarcopenia | (ref) | ||||||
Non‐severe sarcopenia | 1.60 | 0.82–3.10 | 1.09 | 0.56–2.14 | 1.14 | 0.58–2.23 | |
Severe sarcopenia | 3.99 | 2.85–5.59 | 2.04 | 1.38–3.04 | 1.92 | 1.29–2.86 | |
EWGSOP 1/2 | |||||||
No sarcopenia by both EWGSOP 1 and 2 | (ref) | ||||||
Sarcopenia by only EWGSOP 1 | 2.80 | 1.65–4.77 | 2.54 | 1.48–4.35 | 2.46 | 1.43–4.21 | |
Sarcopenia by both EWGSOP 1 and 2 | 4.10 | 2.86–5.87 | 2.20 | 1.47–3.32 | 2.11 | 1.40–3.17 | |
SPS (sarcopenia phenotype score) | |||||||
0 | (ref) | ||||||
1 | 1.67 | 0.78–3.54 | 1.45 | 0.68–3.09 | 1.38 | 0.64–2.94 | |
2 | 4.18 | 2.11–8.27 | 3.00 | 1.48–6.10 | 2.79 | 1.37–5.68 | |
3 | 8.70 | 4.48–16.90 | 4.37 | 2.11–9.05 | 3.86 | 1.85–8.03 |
Model 1: unadjusted; Model 2: age, gender adjusted; and Model 3: age, gender, baseline disability, multimorbidity adjusted. CI, confidence interval; EWGSOP, European Working Group on Sarcopenia in Older People; HR, hazard ratio; ref, reference.