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. 2020 Jan 28;11(2):564–577. doi: 10.1002/jcsm.12535

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© 2020 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Muscle strength of senescence‐accelerated mouse P8 mice upon different treatments at various time points. (A) Twitch force (F0) of COM group was significantly higher than CTL group at month 3 post‐intervention. No significant difference was found in other groups. (B) Tetanic force (Ft) of COM group was significantly higher than CTL group at month 3 with no significant difference detected in other groups. (C) Specific twitch force (SF0) of VIB and COM groups were significantly higher than CTL group at month 3 with no significant difference detected in other groups. (D) Specific tetanic force (SFt) of COM group was significantly higher than CTL group at month 3 with no significant difference detected in other groups. (E) The grip strength of HMB, VIB, and COM groups were significantly higher than CTL group at month 3. *P < 0.05; **P < 0.01; ***P < 0.001. HMB, β‐hydroxy‐β‐methylbutyrate.