FIG 5.

Histatin 5 derivatives exhibit antibacterial activity that is partially associated with self-assembly. Standard growth curves in rich medium over 15 h that were determined using (a) E. coli and (b) S. epidermidis illustrate the higher efficacy of L7F than on dhvar2 (both at 250 μg/ml). The peptides exhibited dose-dependent growth inhibition of (c) E. coli and (d) S. epidermidis exposed to dhvar2 (blue), L7F (red), and a no-peptide control (black).