TABLE 3.

Amino acid changes in colistin-resistant mutants compared to the parental strain

Strain	MIC (μg/ml)	Amino acid change in:
		pmrA	pmrB	Ab19606_02965	miaA	betI_2	iclR	shlB_1	Ptk	aroP_3	pstS
ATCC 19606	1–2
Ab256-1	512	P102R		D106E
Ab256-2	512	P102R		D106E	I221V
Ab256-3	512	P102R		D106E		L147P
Ab256-4	512	P102R		D106E
Ab256-5	512	P102R		D106E
Ab-1	32–64		Q270P				Y49H	R403H	D569N
Ab-2	32–64		Q270P				Y49H	R403H	D569N
Ab-3	32–64		Q270P				Y49H	R403H	D569N
Ab-4	32		Q270P				Y49H	R403H	D569N
Ab-5	32–64		Q270P				Y49H	R403H	D569N
Ab-6	64		T235N				Y49H	R403H	D569N
Ab-12	32		P233S				Y49H	R403H	D569N
Ab-15	32		P233S				Y49H	R403H	D569N
Ab-30	4						Y49H	R403H	D569N
Ab-34	16–32		P233S				Y49H	R403H	D569N	N137S	Y114C
Ab-39	64	I13M					Y49H	R403H	D569N
Ab-51	4						Y49H	R403H	D569N