Table 5.
Performance of novel QPrimer-based rRT-LAMP assay for IV and RSV compared with the reference rRT-PCR assay.
Target | LAMP result | rRT-PCR result |
LAMP sensitivity % (95% CI) | LAMP specificity % (95% CI) | |
---|---|---|---|---|---|
Positive | Negative | ||||
IAV | Positive | 26 | 0 | 89.7 (72.7–97.8) | 100 (95.7–100) |
Negative | 3 | 84 | |||
IBV | Positive | 10 | 0 | 90.9 (58.7–99.8) | 100 (96.5–100) |
Negative | 1 | 102 | |||
A/H1pdm | Positive | 16 | 0 | 88.9 (65.3–98.6) | 100 (96.2–100) |
Negative | 2 | 95 | |||
A/H3 | Positive | 10 | 0 | 90.9 (58.7–99.8) | 100 (96.5–100) |
Negative | 1 | 102 | |||
RSV A | Positive | 17 | 0 | 85.0 (62.1–96.8) | 100 (96.1–100) |
Negative | 3 | 93 | |||
RSV B | Positive | 13 | 0 | 92.9 (66.1–99.8) | 100 (96.3–100) |
Negative | 1 | 99 |