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. 2014 Jul 1;109:97–109. doi: 10.1016/j.antiviral.2014.06.013

Table 7.

SARS Co-V ORF9b.

SARS-CoV p9b
  • •

    Subcellular localization: associated with cytoplasmic vesicular structures

  • •

    Minor structural protein

  • •

    Not required for SARS-CoV replication




Domains and/or regions with characterized functions
  • ■

    Amino acids 46–54: nuclear export signal recognized by exportin 1. Nuclear export of 9b facilitates its degradation in the cytoplasm

  • ■

    Entire 9b protein: induces caspase-dependent apoptosis