Table 4. Associations Between Preeclampsia Exposure and Neurodevelopmental Outcomes Among All Preterm and Term Singleton Birthsa.
Outcome | Exposed to preeclampsia, No. (%) | OR (95% CI) | ||
---|---|---|---|---|
No (n = 1 043 485) | Yes (n = 37 938) | Crude | Adjustedb | |
Cerebral palsy | 1463 (0.1) | 126 (0.3) | 2.37 (1.97-2.84) | 2.26 (1.88-2.73) |
ADHD | 9701 (0.9) | 449 (1.2) | 1.27 (1.15-1.40) | 1.23 (1.12-1.36) |
ASD | 3827 (0.4) | 191 (0.5) | 1.37 (1.19-1.59) | 1.31 (1.12-1.52) |
Epilepsy | 1665 (0.2) | 93 (0.2) | 1.52 (1.24-1.88) | 1.55 (1.25-1.92) |
Intellectual disability | 1592 (0.2) | 80 (0.2) | 1.38 (1.10-1.73) | 1.51 (1.20-1.89) |
Vision or hearing loss | 935 (0.1) | 52 (0.1) | 1.53 (1.15-2.02) | 1.62 (1.22-2.16) |
Abbreviations: ADHD, attention-deficit/hyperactivity disorder; ASD, autism spectrum disorder; OR, odds ratio.
Data are from the Norwegian Medical Birth Registry and linked population registers from January 1, 1991, to December 31, 2009.
Adjusted for sex, year of birth, mother’s age, parity, maternal marital status, maternal and paternal educational levels, and parental immigrant status.