Table 2. Characteristics of Treatment Responders and Partial Responders.
| Variable | Complete responders (n = 51) | Partial responders (n = 36) | P value |
|---|---|---|---|
| Age, median (IQR), y | 18.0 (11-54) | 51.8 (23-62) | .007 |
| Sex, No. (%) | |||
| Female | 44 (86) | 26 (72) | .10 |
| Male | 7 (14) | 10 (28) | |
| Subtype, No. (%) | |||
| Linear | 33 (65) | 12 (33) | .01 |
| Generalized | 13 (25) | 19 (53) | |
| Plaque | 3 (6)a | 4 (11) | |
| Clinical measures, median (IQR) | |||
| mLoSSI | 5 (4-15) | 13 (4-26) | .03 |
| LoSDI | 13 (6-23) | 11 (7-27) | .89 |
| PGA-A | 20 (10-40) | 60 (30-75) | <.001 |
| PGA-D | 38 (20-53) | 20 (10-40) | .03 |
| Treatment, No. (%) | |||
| Methotrexate sodium, with or without corticosteroids | 32 (63) | 16 (44) | NS |
| UV-A1 phototherapy | 15 (29) | 17 (47) | |
| Topical or none | 4 (8) | 3 (8) |
Abbreviations: IQR, interquartile range; LoSDI, Localized Scleroderma Skin Damage Index; mLoSSI, modified Localized Scleroderma Skin Severity Index; NS, not significant; PGA-A, Physician’s Global Assessment of Activity; PGA-D, Physician’s Global Assessment of Damage.
a
Two patients who were complete responders and 1 patient who was a partial responder had indeterminate subtype of morphea.