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. 2020 Apr;8(4):407–419. doi: 10.1016/S2213-2600(19)30469-2

Figure 2.

Figure 2

Tuberculosis scores of the four transcriptional signatures with the highest diagnostic accuracy overall and stratified by HIV status

Red lines represent the score threshold of the maximal Youden index, identified from analysis of all patients. The score difference between individuals with and without tuberculosis was significant for all four signatures in both the total cohort and in HIV-stratified cohort subsets (Mann-Whitney test p<0·0001).