Table 2.
Effect of molecule addition time on potency and efficacy of chloroquine and chlorpromazine.
Conditions | Efficacy |
|||||
---|---|---|---|---|---|---|
Chloroquine |
Chlorpromazine |
|||||
IC50 (μM) | SD | p Value | IC50 (μM) | SD | p Value | |
Pretreatment | 88.9 | 0.11 | ⁎⁎,b | 16.3 | 0.08 | ⁎,b |
Concurrent | 41.2 | 0.02 | nsa | 6.7 | 0.02 | nsa |
Permanent | 37.2 | 0.031 | 8.5 | 0.04 |
IC50: Inhibitory concentration (μM).
ns: Non significative.
Permanent compared to concurrent.
Permanent compared to pre-treatment.
p < 0.05.
p < 0.005.