Fig. 2.
Ribavirin inhibits ZIKV replication in human neuroblastoma and mosquito cells. (A, B) SH-SY5Y cells (A) and C6/36 cells (B) were infected with ZIKV at an MOI of 5 × 10−4 and MOI of 5 × 10−5, respectively. Ribavirin was added on the cells followed by 4 days culture in vitro. The expression of ZIKV RNA was normalized by β-actin (A) or 40S ribosomal protein S17 mRNA (B). ‘ZIKV -’ represents uninfected cells. Data represent mean values ± S.D. of three independent experiments. ***, P < 0.001. **, P < 0.01.