Table 1.
Past and current trials of hepatitis B vaccines.
| Homologous vaccines | ||
| HepT cell | Peptide + adjuvant | Phase 1 |
| INO-1800 | DNA-vaccine | Phase 1 |
| CVI-HBV-002 | DNA-vaccine | Phase 1/2 |
| HB-110/100 | DNA-vaccine | Phase 1a |
| ppdpSC18 | DNA-vaccine | Phase 1/2a |
| HBO2-Vac-AND | DNA-vaccine | Phase 1/2a |
| Theravax | Protein + adjuvant | Phase 1ba |
| GS-4774 | Protein + adjuvant | Phase 2a |
| ePA-44 | Peptide + adjuvant | Phase 2a |
| ABX 203 | Protein | Phase 2/3a |
| TG1050 | Adeno vector vaccine | Phase 2 |
| Heterologous prime –boost vaccines | ||
| pSG2.HBs/MVAHBs | DNA-vaccine + MVA | Phase 1b/2a |
| TherVacB | Protein + MVA (broad) | Preclinical PoC |
Failed.