Fig. 7.

m27f protects mice from lethal HSV-2 infection. (A) Symptoms of genital disease in each group was scored daily as described in the text for 16 days after intravaginally HSV-2 challenge. Data was shown as the mean values of mice in each group. (B) Mice were weighed daily and body weight are expressed as a percentage of the value prior to treatment. Data represent mean ± standard error. (n = 8 animals per group for PBS; n = 7 for all other groups) (C) Survival of mice in each group monitored for indicated days. (n = 8 animals per group for PBS; n = 7 for all other groups). Data were analyzed by Log-rank (Mantel-Cox) test and Gehan-Breslow-Wilcoxon test. * p < 0.05, *** p < 0.001.