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. 2020 Feb 28;9(2):473–480. doi: 10.4103/jfmpc.jfmpc_1097_19

Table 3.

Recommendations of the various researchers, experts, and professional guidelines for the antibiotics prescribed in pediatric dental practice

Author/Year Type of Infection Antibiotic of Choice
Palmer[3] (2006) Acute odontogenic abscess associated with raised axillary temperature and diffuse swelling Amoxicillin (2-3 days, max 5 days)
Phenoxymethyl penicillin (2-3 days, max 5 days)
Penicillin-Allergic Patients:
 Metronidazole (3 days)
 Erythromycin (2-3 days)
 Azithromycin (2-3 days)
Steven Schwartz[1] (2017) Odontogenic infections Early (or first 3 days of infection)
 PenicillinVK, Amoxicillin
 Clindamycin
 Cephalexin (Or other first generation cephalosporin)
No improvement in 24-36 h
 Clindamycin
 Amoxicillin/clavalunic acid (Augmentin)
Penicillin allergy:
 Clindamycin
 Cephalexin
 Clarithromycin
Late (>3 days)
 Clindamycin
 PenicillinVK-
 Metronidazole/Amoxicillin-Metronidazole
Penicillin allergy:
 Clindamycin
AAPD Guidelines[35,36] Acute facial swelling of dental origin Penicillin derivatives remain the empirical choice for odontogenic infections; however, consideration of additional adjunctive antimicrobial therapy (metronidazole) can be given where there is anaerobic bacterial involvement.
Cephalosporins could be considered as an alternative choice for odontogenic infections.
Dar Odeh et al.[4] (2018) Cellulitis Amoxicillin (2-3 days, max 5 days)
OR
Phenoxymethyl penicillin (2-3 days, max 5 days)
Recommended Antibiotic Regimen for Penicillin-Allergic Patient:
 Metronidazole (3 days)
 OR
 Azithromycin
 OR
 Clarithromycin (7 days)