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. 2005 Apr 28;67(1):18–23. doi: 10.1016/j.antiviral.2005.02.007

Table 1.

Effects of plant extracts on SARS-CoV

Plant extract Family Part used Solvent CC50a Viral strain
BJ-001
BJ-006
EC50b SIc EC50b SIc
Lycoris radiata Amaryllis Stem cortex Ethanol 886.6 (±35.0) 2.4 (±0.2) 370 2.1 (±0.2) 422
Artemisia annua Compositae Whole plant Ethanol 1053.0 (±92.8) 34.5 (±2.6) 31 39.2 (±4.1) 27
Pyrrosia lingua Polypodiaceae Leaf Chloroform 2378.0 (±87.3) 43.2 (±14.1) 55 40.5 (±3.7) 59
Lindera aggregate Lauraceae Root Ethanol 1374.0 (±39.0) 88.2 (±7.7) 16 80.6 (±5.2) 17



Interferon alpha >100,000 (±710.1) 660.3 (±119.1) >151 587.2 (±39.0) >170
a

Determined as the concentration of the compounds that reduced the cell viability to 50% of control (cells without addition of compound). Each represents the mean value from three independent experiments. The unit for CC50 values shown in the table is μg/ml except interferon alpha, which is IU/ml.

b

Determined as the concentration of the compounds needed to inhibit CPE to 50% of control value (cells without viral infection). Each represents the mean value from three independent experiments. The unit for EC50 values shown in the table is μg/ml except interferon alpha, which is IU/ml.

c

Selectivity index (CC50/EC50).