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. 2005 Apr 28;67(1):18–23. doi: 10.1016/j.antiviral.2005.02.007

Table 2.

Effects of components isolated from L. radiata on SARS-CoV (BJ-001)

Samples EC50a CC50b SIc
Total alkaloid from Lycoris radiata 1.0 (±0.1) 93.9 (±7.4) 94
Commercial lycorine 48.8 (±3.6) 43210.0 (±2101.0) 885
Isolated lycorine from Lycoris radiata 15.7 (±1.2) 14980.0 (±912.0) 954
a

Determined as the concentration of the compounds needed to inhibit CPE to 50% of control value (cells without viral infection). Each value represents the mean ± S.D. from three independent experiments. The unit for EC50 values shown in the table is μg/ml for total alkaloid from L. radiata, and is nM for both forms of lycorine.

b

Determined as the concentration of the compounds that reducing the cell viability to 50% of control (cells without addition of compound). Each value represents the mean ± S.D. from three independent experiments. The unit for CC50 values shown in the table is μg/ml for total alkaloid from L. radiata, and is nM for both forms of lycorine.

c

Selectivity index (CC50/EC50).