Table 3.

Generalized estimating equation models for risk of cryptosporidiosis (oocysts shedding or clinical signs) in neonatal calves treated either with halofuginone lactate or untreated and maintained in either individual pens or in group pens.

Outcome	Experimental groups	Variable	Coefficient	p-value	95% confidence interval
					Lower limit	Upper limit
PCRa detection	Individual pen	Halofuginone vs placebo	−1.36	<0.001	−1.95	−0.78
	Group pen	Halofuginone vs placebo	−0.30	0.12	−0.66	0.07
	Halofuginone	Individual pen vs group pen	−1.16	<0.001	−1.73	−0.59
	Placebo	Individual pen vs group pen	−0.11	0.56	−0.48	0.26
	All calves	Interaction halofuginone and individual pen	−1.02	0.004	−1.72	−0.32
IFA OPGb	Individual pen	Halofuginone vs placebo	−3.18	<0.001	−3.18	−3.17
	Group pen	Halofuginone vs placebo	−2.54	<0.001	−2.55	−2.54
	Halofuginone	Individual pen vs group pen	−1.31	<0.001	−1.31	−1.31
	Placebo	Individual pen vs group pen	−0.68	<0.001	−0.68	−0.68
	All calves	Interaction halofuginone and individual pen	−0.63	<0.001	−0.64	−0.63
Diarrhoea	Individual pen	Halofuginone vs placebo	−1.67	<0.001	−2.56	−0.77
	Group pen	Halofuginone vs placebo	−0.83	0.016	−1.50	−0.15
	Halofuginone	Individual pen vs group pen	−0.93	0.08	−1.97	0.12
	Placebo	Individual pen vs group pen	−0.11	0.65	−0.61	0.38
	All calves	Interaction halofuginone and individual pen	−0.82	0.15	−1.94	0.29

Significant p-value <0.05.

^aPolymerase chain reaction.

^bNumber of oocyst per gram of faeces detected by immunofluorescence assay.