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. 2015 Jun 27;197:170–179. doi: 10.1016/j.ijcard.2015.06.076

Fig. 2.

Fig. 2

Regulatory function of GLP-1 on glucose metabolism.

In response to meal intake, GLP-1 is released by L cells distributed throughout the gastrointestinal tract (GI Tract). GLP-1 acts on GLP-1 receptor (GLP-1R) that is expressed in various organs and mediates multiple processes to maintain glucose homeostasis.