Table 1.

Antiviral activity of Houttuynia cordata aerial part-derived materials against porcine epidemic diarrhea virus in Vero cells.

Test material	IC50a	CC50b	TIc
Methanolic extract	82.2	1036.0	12.6
Haxane fraction	4.5 ± 0.53	64.7	14.4
Ethyl acetate fraction	4.8 ± 0.37	62.1	13.1
Butanol fraction	46.3 ± 7.9	>100	>2.2

Results are presented as the mean IC₅₀ values obtained from three independent experiments carried out in triplicate ±S.D.

^aConcentration required to inhibit virus-induced CPE by 50% (μg/mL).

^bConcentration required to reduce cell growth by 50% (μg/mL).

^cTherapeutic index = CC₅₀/IC₅₀.