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Teicoplanin aglycon derivatives with eliminated amino acids 1 and 3 
| LCTA | Code no. | X | Y | HIV-1 (CEM) |
FIPV (CRFK) |
SARS-CoV (Vero) |
|||
|---|---|---|---|---|---|---|---|---|---|
| EC50 (μM) | IC50 (μM) | EC50 (μM) | CC50 (μM) | EC50 (μM) | CC50 (μM) | ||||
| 913 | 172 | H | H | 25 | >500 | >80 | >80 | >80 | >80 |
| 961 | 173 | H | Boc | 17.5 | >250 | 23 ± 8 | >80 | 43 ± 5 | >80 |
| 962 | 174 | CH2NHAdam-2 | Boc | 17 ± 3 | 240 ± 13 | 35 ± 30 | >80 | 61 ± 45 | >80 |
| 963 | 175 | CH2NHAdam-2 | H | 17 ± 3 | >250 | 19 ± 0 | >50 | >80 | >80 |
