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Teicoplanin aglycon derivatives with the disrupted bond between amino acids 1 and 2 
| LCTA | Code no. | X | HIV-1 (CEM) |
FIPV (CRFK) |
SARS (Vero) |
|||
|---|---|---|---|---|---|---|---|---|
| IC50 (μM) | EC50 (μM) | IC50 (μM) | EC50 (μM) | IC50 (μM) | EC50 (μM) | |||
| 968 | 176 | H | 15 | >250 | 48 ± 46 | >80 | 40 ± 5 | >80 |
| 969 | 177 | CH2NHAdam-2 | 13 ± 9.9 | 242 ± 11 | 22 ± 3 | >80 | 45 ± 13 | >80 |
