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Apparent KD value for IIa-gp120 interaction.
| Compound | Ka (103) (1/M.s) | Ka (10−3) (1/s) | KD (10−6) (M) |
|---|---|---|---|
| IIa | 7.14 ± 2.41 | 2.26 ± 0.34 | 0.34 ± 0.86 |
| PRM-A | 2.76 ± 1.00 | 17.16 ± 4.21 | 6.92 ± 25.99 |
Average and standard deviation of kinetic parameters obtained from three replicate SPR experiments measuring the binding response between gp120 and IIa/PRM-A.
