Table 3.

Association between medication persistence and cardiovascular mortality 5 years within cohort entry.

	Hazard ratio (95% C.I.)	p
Age
< 50	1.00 (reference)	< 0.001
50–59	2.28 (1.83–2.84)
60–69	5.65 (4.67–6.83)
≥ 70	15.79 (13.24–18.82)
Gender
Male	1.00 (reference)	< 0.001
Female	0.79 (0.74–0.85)
Public assistance
No	1.00 (reference)	< 0.001
Yes	1.15 (1.07–1.24)
Proportion of Days Covered (PDC)
< 40%	1.00 (reference)
40–79%	0.46 (0.41–0.52)	< 0.001
≥ 80%	0.91 (0.85–0.98)	0.012
First prescription
Thiazide diuretics	1.00 (reference)
ACEIs	1.31 (1.13, 1.52)	< 0.001
β-Blockers	1.02 (0.89–1.18)	0.738
CCBs	1.21 (1.06–1.38)	0.005

ACEIs: angiotensin converting enzyme inhibitors; CCBs: calcium channel blocker.