Table 5.
Logistic regression model results from a double-blind block-randomized clinical trial on the effect of treatment with zinc methionine (Met) or zinc oxide (ZO) compared to a placebo on microbiological curea in neonatal Holstein calves with diarrhea.
| Treatmentb | Fecal ELISA positive at enrollment (n) | Fecal ELISA negative at exit (n) | β | SE | OR | 95% C.I. |
P-value | |
|---|---|---|---|---|---|---|---|---|
| Lower | Upper | |||||||
| Placebo | 23 | 9 | Reference | |||||
| Zinc Met | 24 | 12 | 0.442 | 0.591 | 1.55 | 0.49 | 4.95 | 0.455 |
| ZO | 21 | 4 | −1.01 | 0.701 | 0.37 | 0.09 | 1.45 | 0.152 |
a
Microbiological cure defined as fecal ELISA test negative for E. coli K99, Cryptosporidium spp., rotavirus, and coronavirus at exit from trial.
b
Treatment: Placebo = zinc-free oral rehydration solution (ORS); zinc Met = 80 mg of zinc/2 L of ORS (381.5 mg of zinc Met); ZO = 80 mg of zinc/2 L of ORS (99.7 mg of ZO).