Table 6.
Logistic regression model results from a double-blind block-randomized clinical trial on the effect of treatment with zinc methionine (Met) or zinc oxide (ZO) compared to a placebo on microbiological curea in neonatal Holstein calves with diarrhea and Cryptosporidium spp. ELISA positive at enrollment.
| Treatmentb | Cryptosporidium spp. positiveat enrollment (n) | Cryptosporidium spp. negative at exit (n) | β | SE | OR | 95% C.I. |
P-value | |
|---|---|---|---|---|---|---|---|---|
| Lower | Upper | |||||||
| Placebo | 5 | 1 | Reference | |||||
| Zinc Met | 5 | 4 | 2.773 | 1.581 | 16.00 | 0.72 | 354.80 | 0.080 |
| ZO | 10 | 1 | −0.811 | 1.537 | 0.44 | 0.02 | 9.03 | 0.598 |
a
Microbiological cure defined as fecal ELISA test negative for E. coli K99, Cryptosporidium spp., rotavirus, and coronavirus at exit from trial.
b
Treatment: Placebo = zinc-free oral rehydration solution (ORS); zinc Met = 80 mg of zinc/2 L of ORS (381.5 mg of zinc Met); ZO = 80 mg of zinc/2 L of ORS (99.7 mg of ZO).