. 2010 Jan 25;1803(4):507–519. doi: 10.1016/j.bbamcr.2010.01.011

Table 1.

Comparison of the structural elements of cellular transport vesicles with two enveloped viruses, influenza and human immunodeficiency virus.

	Cellular vesicles	Influenza virus	Human immunodeficiency virus (HIV)
Transmembrane proteins	v-SNARE (different variants for each transport step)	Hemagglutinin (HA, attachment and fusion), neuraminidase (NA, detachment after budding)	gp160 with subunits gp120 (attachment) and gp41 (fusion)
Task: attachment to and fusion with acceptor membrane	v-SNARE (different variants for each transport step)		gp160 with subunits gp120 (attachment) and gp41 (fusion)
Coat proteins	Clathrin or COP I or COP II	Matrix protein (M1)	gag (four subunits)
Task: polymerization, budding, morphology	Clathrin or COP I or COP II	Matrix protein (M1)	gag (four subunits)
Cargo	Proteins: membrane or lumenal	Genome plus associated proteins: arranged in eight different ribonucleoparticles (vRNP)	Genome plus associated proteins: arranged in one segment
Task: signalling to initiate budding	Proteins: membrane or lumenal		Genome plus associated proteins: arranged in one segment
Membrane bilayer	Derived from different donor membranes, various composition	Derived from subdomains of the plasma membrane, enriched in raft-lipids	Derived from subdomains of the plasma membrane, enriched in raft-lipids
Task: recruitment of coat, envelope formation	Derived from different donor membranes, various composition