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. 2010 Jan 25;1803(4):507–519. doi: 10.1016/j.bbamcr.2010.01.011

Table 1.

Comparison of the structural elements of cellular transport vesicles with two enveloped viruses, influenza and human immunodeficiency virus.

Cellular vesicles Influenza virus Human immunodeficiency virus (HIV)
Transmembrane proteins v-SNARE (different variants for each transport step) Hemagglutinin (HA, attachment and fusion), neuraminidase (NA, detachment after budding) gp160 with subunits gp120 (attachment) and gp41 (fusion)
Task: attachment to and fusion with acceptor membrane
Coat proteins Clathrin or COP I or COP II Matrix protein (M1) gag (four subunits)
Task: polymerization, budding, morphology
Cargo Proteins: membrane or lumenal Genome plus associated proteins: arranged in eight different ribonucleoparticles (vRNP) Genome plus associated proteins: arranged in one segment
Task: signalling to initiate budding
Membrane bilayer Derived from different donor membranes, various composition Derived from subdomains of the plasma membrane, enriched in raft-lipids Derived from subdomains of the plasma membrane, enriched in raft-lipids
Task: recruitment of coat, envelope formation