Fig. 1.

Antiviral activity of PD and RW peptides on VV during the pre-infection stage. WR strain of VV was incubated with PD and RW peptides at 100 μg/ml and 10 μM concentration, respectively, for 2 h at RT and titers were measured by counting plaques on B-SC-1 cells. Since PD peptides were of uniform length (15 aa) they were constituted in μg/ml whereas RW peptides though were of varying length (2, 4, 6, 8 and 10 aa) and hence expressed in μM concentrations. These two different concentration expression units were maintained to be consistent with our previously published work (Mohan et al., 2009a). VV infection without the peptides was included as control. PD3, PD4 and RW3 peptides demonstrate significant (p < 0.05, indicated by *) reduction in viral titers.