Table 1.

Tissue distribution of the novel Ang II/III binding site.

	Brain	Testis	Epididymis
Bmax	139 ± 11.5	384 ± 70.7	80.8 ± 15.5
KD	1.85 ± 0.15	3.69 ± 0.77	5.89 ± 1.23
	n = 32 (32)	n = 11 (12)	n = 7 (7)
	Spleen	Pancreas	Lung
Bmax	72.9 ± 16.2	63.1 ± 9.9	56.9 ± 7.6
KD	2.87 ± 0.82	3.03 ± 0.75	2.55 ± 0.62
	n = 8 (10)	n = 10 (11)	n = 6 (9)
	Heart	Skeletal muscle	Seminal vesicles
Bmax	11.9 ± 4.8	13.3 ± 3.2	265 ± 36.5
KD	0.86 ± 0.44	3.15 ± 1.70	3.81 ± 1.63
	n = 3 (11)	n = 5 (10)	n = 3 (8)

Saturation binding analyses of ¹²⁵I-SI Ang II binding to the novel Ang II/Ang III binding site in mouse forebrain, testis, spleen, pancreas, skeletal muscle, heart, lung, epididymis, and seminal vesicles. B_max (fmol/mg protein) and K_D (nM) (± SEM) values reported do not include samples for which B_max or K_D was not significantly different from zero (95% confidence interval from the saturation isotherm was zero or less from the non-linear regression analysis to the equation B = B_max[D]/(K_D + [D]) where [D] = concentration of ¹²⁵I SI Ang II) [n = samples used (total samples)]. Values shown in italics are for tissues and conditions in which binding was not reliably detectable in half or more of the assays.