Table 4.

Experiment 4: detectable viral load (viral genomic RNA) expressed as average cycle threshold values^a ± standard error in broiler chickens challenged with IBV at various times after treatment with QR448(a) at 1 day of age.

Treatment group	Challengeb times post-treatment
	2 h	4 h	6 h	12 h	1 day	2 days	4 days	7 days
QR448(a) + IBV	24.58 ± 0.78	24.15 ± 0.61	23.42 ± 0.74	21.86 ± 0.52	22.00 ± 0.79	25.43 ± 0.57	24.27 ± 0.96	25.14 ± 1.16
QR448(a)	Negc	Neg	Neg	Neg	Neg	Neg	Neg	Neg
IBV	24.24 ± 0.73	24.78 ± 0.52	22.28 ± 0.67	22.83 ± 0.67	21.06 ± 1.25	24.19 ± 0.89	24.19 ± 0.87	23.66 ± 1.07
Negative control	Neg				Neg	Neg	Neg	Neg

^aLarger numbers = less virus. Average values were not statistically significant (Student's t-test).

^bEach bird was given 1 × 10^3.5 EID₅₀ of the Mass41 strain of IBV intranasally, and necropsied 5 days post-challenge.

^cNegative.