Table 1.

MERS-CoV entry inhibitors targeting different parts in spike proteins.

Inhibitors	Property	Target	Assay	IC50 (μg/ml)	Reference
sDPP4	Protein	RBD in S1	Pseudovirus	∼10	Raj et al. (2014)
Mersmab1 IgG	Mouse mAb	RBD in S1	Pseudovirus	∼0.10	Du et al. (2014)
Mersmab1 IgG	Mouse mAb	RBD in S1	Live virus (CPE)	∼1.20	Du et al. (2014)
m336 IgG	Human mAb	RBD in S1	Pseudovirus	0.005	Ying et al. (2014)
m336 IgG	Human mAb	RBD in S1	Live virus (CPE)	0.07	Ying et al. (2014)
MERS-4 IgG	Human mAb	RBD in S1	Pseudovirus	0.056	Jiang et al. (2014)
MERS-4 IgG	Human mAb	RBD in S1	Live virus (CPE)	0.50	Jiang et al. (2014)
3B11 scFvFc	Human mAb	RBD in S1	Live virus (CPE)	1.83	Tang et al. (2014)
3B11 IgG	Human mAb	RBD in S1	Live virus (CPE)	3.5	Tang et al. (2014)
HR2P	Peptide	HR1 in S2	Cell–cell fusion	3.314	Lu et al. (2014)
HR2P	Peptide	HR1 in S2	Live virus (CPE)	2.485	Lu et al. (2014)
HR2P-M2	Peptide	HR1 in S2	Cell–cell fusion	2.278	Lu et al. (2014)