Skip to main content
. 2011 Jan 4;156(1):72–80. doi: 10.1016/j.virusres.2010.12.020

Table 1.

Differences in the predicted amino acid sequences, virulence in cats, and cell proliferation between strain FIPV 79-1146 and mar mutant viruses.

Virus ORF 1ab ORF 2 (S)
ORF 3abc ORF 4 (E) ORF 5 (M) ORF 6 (N) ORF 7
Pathogenicity in cats Proliferation of cells
S1 S2 a b Monocyte Macrophage
FIPV 79-1146 * * * * * * * * * High High High
mar 6-4-2.C2 * T → K (554)a,b * * * * * * * High High High
mar 7-4-1.C2 * A → V (480)a * * * * * * * High High High
R → C (647)a,b
mar 6-4-2.7-4-1 * A → V (480)a * * * * * * * Moderate to low Moderate to high Moderate to low
T → K (554)a,b
R → K (647)a,b
mar 5-7-2.C1 * L → S (589)a,b * * * * * * Deleted (N-terminal 29aa) Low High High
mar 5-7-2.C2 * M → T (542)a,b * * * * * * Deleted (N-terminal 29aa) Low Low Low
L → S (589)a,b
mar 5-7-2.7-4-1 * M → T (542)a,b * * * * * * Deleted (N-terminal 29aa) Low Low Low
L → S (589)a,b
R → L (647)a,b

The predicted amino acid sequence conserved between strain FIPV 79-1146 and FIPV mar mutant virus indicated by asterisks.

a

These information were referred to the article by Kida et al. (1999).

b

Amino acids present in the neutralizing epitope (A1 and A2 sites) of FIPV 79-1146 (Corapi et al., 1995, Kida et al., 1999).