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Nucleoside analogs inhibiting norovirus RdRp. (A) Structure and inhibition potency of ribavirin, T-705/Favipiravir, and T-705 ribonucleoside triphosphate analogs T-1106-TP and 2CM-T-1106-TP. (B) Structure and inhibition potency of 2′-C-methyl-cytidine (2-CMC) and 2′-C-methyl-2′-fluroro-cytidine (2′F-2′C-Me-C).
