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. 2008 May 22;38(4):919–929. doi: 10.1016/j.cvsm.2008.02.010

Table 2.

Specific viruses that are screened for in bovine serum (calf and fetal origin) and porcine trypsin used in production of veterinary biologics

Bovine serum Trypsin

  • Adenovirus (groups 1 and 2)

  • Akabane

  • Bovine coronavirus

  • Bovine ephemeral fever

  • Bluetongue virus

  • Bovine leukosis

  • Bovine immunodeficiency virus

  • Bovine respiratory syncytial virus

  • Bovine viral diarrhea virus

  • Rift valley fever virus

  • Vesicular stomatitis virus (Indiana and New Jersey)

  • Bovine herpesviruses type 1, 2, 4

  • Malignant catarrhal fever

  • Parainfluenza virus type 3

  • Bovine polyomavirus

  • Porcine adenoviruses

  • African swine fever virus

  • Pseudorabies virus

  • Hemagglutinating encephalomyelitis virus

  • Bovine viral diarrhea virus

  • Hog cholera virus

  • Encephalomyocarditis virus

  • Swine influenza virus

  • Porcine parvovirus

  • Porcine respiratory and reproductive syndrome

  • Vesicular stomatitis virus (Indiana and New Jersey)

  • Transmissible gastroenteritis

  • Respiratory variant (coronavirus)

  • Porcine enterovirus

  • Vesicular exanthema virus

  • Swine vesicular virus

Modified from Merten OW. Virus contamination of cell cultures—a biotechnological view. Cytotechnology 2002;39(2):101; with permission.